Children and adolescents
Pediatric vasculitis with organ threat
Childhood ANCA vasculitis, PAN or Takayasu with kidney, lung, gut, nerve or limb ischemia.
What to look for
- ANCA vasculitis: pulmonary hemorrhage, rapidly progressive glomerulonephritis
- PAN: painful nodules, livedo, testicular or abdominal pain, hypertension
- Takayasu: claudication, absent pulses, hypertension, bruits in an adolescent
What to do
- Contact pediatric rheumatology directly. Organ threat needs the ED or admission.
- Send ANCA (PR3/MPO), CBC, metabolic panel, urinalysis with microscopy, ESR/CRP and BP. Get CTA or MRA for large-vessel disease.
- Consider DADA2 testing in a child with PAN-like disease or stroke.
About this urgency level
Call rheumatology directly. Many of these need the emergency department or admission, and treatment often starts before the specialist visit.
Timeframes are typical targets. Local pathways, capacity and clinical judgment come first.